RecruitingNot a traditional drug phaseinterventionalRules rewrite

Not a traditional drug phase: testing Ropivacaine 0.2% Injectable Solution for Knee Osteoarthritis

This prospective randomly assigned controlled trial aims to compare the analgesic how well it works and safety of three adjuvant strategies for ultrasound-guided Adductor Canal Block (ACB) and iPACK block in patients undergoing elective total knee arthroplasty under spinal anesthesia. All participants will receive standardized spinal anesthesia with 0.5% ropivacaine combined with ACB and iPACK blocks using 0.2% ropivacaine.

Official registry: https://clinicaltrials.gov/study/NCT07677215 · Poznan University of Medical Sciences · enrollment listed as 120

What this phase means

This study does not use the classic phase 1–4 drug ladder. It may be a device, a behavior program, a surgery timing study, or an early feasibility test.

Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

What the registry says happens

If you join, the listed intervention(s) are Ropivacaine 0.2% Injectable Solution, Dexamethasone, or Dexmedetomidine. The registry lists allocation as randomized. This prospective randomly assigned controlled trial aims to compare the analgesic how well it works and safety of three adjuvant strategies for ultrasound-guided Adductor Canal Block (ACB) and iPACK block in patients undergoing elective total knee arthroplasty under spinal anesthesia.

They plan to enroll about 120 people at 2 sites. Taking part typically means taking a study drug (or dummy pill) plus check-ins.

Official title (unrewritten)

Comparison of the Efficacy and Safety of Three Adjuvant Strategies for ACB and iPACK Blocks in Patients Undergoing Elective Total Knee Arthroplasty: A Prospective, Randomized Clinical Trial

Interventions: Ropivacaine 0.2% Injectable Solution, Dexamethasone, Dexmedetomidine

Primary outcome (registry wording): Total postoperative opioid consumption during the first 48 hours after surgery

Who it is for (from inclusion criteria)

Ages 60 Years to 100 Years
Age between 60 and 100 years
Scheduled for elective primary unilateral total knee arthroplasty
American Society of Anesthesiologists (ASA) physical status I-III
Eligibility for spinal anesthesia and ultrasound-guided regional anesthesia according to institutional standards

Who the registry excludes

Known allergy or hypersensitivity to ropivacaine, dexamethasone, dexmedetomidine, or any study-related medication
Contraindications to spinal anesthesia or peripheral nerve blocks
Coagulation disorders or anticoagulant therapy preventing safe regional anesthesia
Infection at the planned puncture site or systemic infection
Severe neurological disorders affecting lower limb sensory or motor function
Severe hepatic, renal, or uncontrolled cardiovascular disease
Clinically significant bradycardia or advanced atrioventricular conduction abnormalities

Public study contact (from the registry)

Malgorzata Reysner, MD PhD

+48 61 8310122

mreysner@ump.edu.pl

Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.

Sites listed on ClinicalTrials.gov

2 listed

The John Paul II Catholic University of Lublin — Lublin, Poland (recruiting)
Poznan University of Medical Sciences — Poznan, Poland (recruiting)

Related recruiting trials in this snapshot

RecruitingNot a traditional drug phaseNew York, New York

Not a traditional drug phase: Ensure for Osteoarthritis

This study wants to determine the effect on hematological markers of nutritional intervention on nutritionally deficient patients following total joint replacement surgery.

NCT04210284 · Official ClinicalTrials.gov record · NYU Langone Health

RecruitingNot a traditional drug phaseClermont-Ferrand

Not a traditional drug phase: Development of a screening algorithm designed to determine a "dysmobility" profile in patients with chronic illness. for Joint Osteoarthritis

Chronic illness is a public health issue and mobility loss is frequent in this population. Among its' multiple physical and psychological consequences, increased mortality and cardiovascular morbidity seem the main concern.

NCT04375280 · Official ClinicalTrials.gov record · University Hospital, Clermont-Ferrand

RecruitingNot a traditional drug phaseHelsinki

Not a traditional drug phase: Trapeziectomy for Thumb Osteoarthritis

A multi-center randomly assigned compared with a dummy treatment clinical trial which determines the how well it works of trapeziectomy in patients with persistent painful osteoarthritis at the base of the thumb. The primary outcome is patient reported evaluation of pain and function of the wrist and hand at 6 months after the randomization to treatment group.

NCT05127005 · Official ClinicalTrials.gov record · Tampere University Hospital

FAQ about this NCT record

Is NCT07677215 still recruiting?

The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.

What phase is NCT07677215?

Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

Can PlainTrials tell me if I qualify for NCT07677215?

No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.

How to read a ClinicalTrials.gov record · Questions to ask the coordinator · Glossary