Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
PlainTrials
RecruitingPhase 2interventionalRules rewrite

Phase 2: testing SUN-627 for Primary Progressive Multiple Sclerosis

The goal of this Phase 2 clinical trial is to investigate the whether it is safe and how hard side effects are to live with of SUN-627 in men and women aged 18-70 years old with a diagnosis of non-active SPMS/PPMS.

Official registry: https://clinicaltrials.gov/study/NCT07840326 · Sundance Biosciences, Inc. · enrollment listed as 20

What this phase means

Phase 2: researchers already know a roughly safe dose (from phase 1). This stage asks whether the treatment actually helps the condition, and watches side effects more closely.

Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

What the registry says happens

If you join, the listed intervention(s) are SUN-627, or Placebo. The registry lists allocation as randomized. The goal of this Phase 2 clinical trial is to investigate the whether it is safe and how hard side effects are to live with of SUN-627 in men and women aged 18-70 years old with a diagnosis of non-active SPMS/PPMS.

They plan to enroll about 20 people at 7 sites. Taking part typically means taking a study drug (or dummy pill) plus check-ins.

Official title (unrewritten)

A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Study of SUN-627 to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Impact on Measures of Neuroinflammation in the Central Nervous System in Participants With Non-Active Progressive Multiple Sclerosis (SPMS/PPMS)

Interventions: SUN-627, Placebo

Primary outcome (registry wording): Incidence of treatment-emergent adverse events (TEAEs) and serious adverse events (SAEs) compared to placebo

Who it is for (from inclusion criteria)

  • Ages 18 Years to 70 Years
  • Aged 18-70, inclusive
  • Diagnosis of PPMS or non-active SPMS
  • No MS relapses in the past 2 years
  • Evidence that MS has continued to get worse over time
  • A level of disability that fits the study requirements

Public study contact (from the registry)

Chetan Gandhy, MD

650-442-3187

clinicaltrials@sundancebio.com

Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.

Sites listed on ClinicalTrials.gov

7 listed

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FAQ about this NCT record

Is NCT07840326 still recruiting?

The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.

What phase is NCT07840326?

Phase 2. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

Can PlainTrials tell me if I qualify for NCT07840326?

No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.

How to read a ClinicalTrials.gov record · Questions to ask the coordinator · Glossary