The purpose of this Phase 2a/b study is: 1. to measure the how well it works, whether it is safe and how hard side effects are to live with of DDY391 in participants with psoriatic arthritis (PsA).
Official registry: https://clinicaltrials.gov/study/NCT07801495 · Novartis Pharmaceuticals · enrollment listed as 220
Phase 2: researchers already know a roughly safe dose (from phase 1). This stage asks whether the treatment actually helps the condition, and watches side effects more closely.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
If you join, the listed intervention(s) are DDY391, or Placebo. The registry lists allocation as randomized. The purpose of this Phase 2a/b study is: 1.
They plan to enroll about 220 people at 8 sites. Taking part typically means taking a study drug (or dummy pill) plus check-ins.
A Randomized, Double-blind, Placebo-controlled, Multicenter Phase 2a/b Study Assessing the Efficacy, Safety and Tolerability of DDY391 in Participants With Active Moderate to Severe Psoriatic Arthritis
Interventions: DDY391, Placebo
Primary outcome (registry wording): Part A: Number of participants achieving American College of Rheumatology 50 (ACR50) response
Novartis Pharmaceuticals
Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.
Treatment of moderate to severe Psoriasis (Pso) and Psoriasis-Arthritis (PsA) is largely confined to systemic therapy in Germany. Systemic therapy includes conventional systemic therapy (e.g.
NCT01848028 · Official ClinicalTrials.gov record · Universitätsklinikum Hamburg-Eppendorf
Glucocorticoids remain to be among the most important and most frequently used anti-inflammatory and immunosuppressive or immune-modulatory acting drugs to treat rheumatic (and other) diseases. Unfortunately, glucocorticoids also exert undesired effects, especially if higher dosages have to be given over longer periods of time.
NCT02719314 · Official ClinicalTrials.gov record · Prof Dr Frank Buttgereit
The purpose of this pediatric study is to measure the drug levels, how well it works and safety of Deucravacitinib in children and adolescent participants aged 4 to \<18 years with moderate to severe plaque psoriasis. This study includes two cohorts; Cohort 1 (age 12 to \<18 years) and Cohort 2 (age 4 to \<12 years), with two parts; for each cohort.
NCT04772079 · Official ClinicalTrials.gov record · Bristol-Myers Squibb
The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.
Phase 2. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.
How to read a ClinicalTrials.gov record · Questions to ask the coordinator · Glossary