What this phase means
Phase 2: researchers already know a roughly safe dose (from phase 1). This stage asks whether the treatment actually helps the condition, and watches side effects more closely.
Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.
What the registry says happens
If you join, the listed intervention(s) are Psilocybin, or Cognitive Training. The registry lists allocation as randomized. Background: Normal aging, as well as dementias such as Alzheimer s disease, can cause changes in the brain that affect memory, attention, and thinking.
They plan to enroll about 200 people at Baltimore. Taking part typically means taking a study drug (or dummy pill) plus check-ins.
Official title (unrewritten)
Neuroplasticity Enhancement From Cognitive Training Reinforced by Psilocybin (NECTAR) in Aging and Alzheimer's Disease
Interventions: Psilocybin, Cognitive Training
Primary outcome (registry wording): Determine whether psilocybin enhances neuroplasticity (Neuroplasticity Composite Score (NPCS))