Not medical advice. This website is not medical advice, a diagnosis, a match to a trial, or a recommendation to join a study. Listings are plain-English rewrites of public ClinicalTrials.gov records. Whether a site is still enrolling, and whether you qualify, can only be confirmed by the study team and your clinician. Source registry: ClinicalTrials.gov. Editorial rules: methodology.
PlainTrials
RecruitingNot a traditional drug phaseobservationalRules rewrite

Not a traditional drug phase: RNA sequencing for Amyotrophic Lateral Sclerosis

Genetic diagnosis of Amyotrophic Lateral Sclerosis (ALS) could identify the origin of the disease, potentially allowing the patient to pursue targeted/gene therapy. However, many familial forms of ALS are genetically undiagnosed, either because no variant has been detected in the genes of interest, or because the detected variant(s) have uncertain significance.

Official registry: https://clinicaltrials.gov/study/NCT06083584 · Centre Hospitalier Universitaire de Nīmes · enrollment listed as 192

What this phase means

This is an observational study. You are not assigned a new experimental drug. Researchers measure what already happens in your care or in daily life.

Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

What the registry says happens

This listing is observational (StudyType). The registry does not assign a new experimental drug as the study intervention.

They plan to enroll about 192 people at 7 sites. Taking part typically means study visits and measurements plus check-ins.

Official title (unrewritten)

Development of Targeted RNA-Seq for Amyotrophic Lateral Sclerosis Diagnosis

Interventions: RNA sequencing

Primary outcome (registry wording): Concordance between the RNA-Seq results (index text) versus RT-PCR followed by Sanger sequencing (reference technique) on positive plus negative controls

Who it is for (from inclusion criteria)

  • Ages 18 Years to any
  • Have a prescription for a genetic diagnosis of ALS (or familial hypercholesterolemia for the control cohort)
  • The patient must be a member or beneficiary of a health insurance plan

Public study contact (from the registry)

Claire Guissart

04 66 68 32 07

claire.guissart@chu-nimes.fr

Published on ClinicalTrials.gov. Contact them as a possible participant. They decide eligibility.

Sites listed on ClinicalTrials.gov

7 listed

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FAQ about this NCT record

Is NCT06083584 still recruiting?

The sponsor posted status “Recruiting” on ClinicalTrials.gov at last ingest. Sites can pause independently. Confirm with the official record and the listed contact.

What phase is NCT06083584?

Not a traditional drug phase. Phase labels are FDA/ICH categories applied to the registry Phase field. They are not a finding that this study succeeded.

Can PlainTrials tell me if I qualify for NCT06083584?

No. The inclusion and exclusion lists on this page are readable extracts of the public eligibility block. Only the study team can screen you.

How to read a ClinicalTrials.gov record · Questions to ask the coordinator · Glossary